High Potency Serrapeptase, Doctor's Best, 270 Caps

Benefits

• May help support a normal inflammatory response in the body.
• May help relieve minor discomfort and swelling following minor injury or exercise.
• May help support recovery after physical strain.
• May help support clear airways and comfortable breathing during seasonal changes.
• May help support healthy mucus thickness in the airways.
• May help support throat comfort.

What people commonly use it for

• Minor swelling and soreness after exercise or injury (Some clinical studies suggest benefit)
• Throat soreness (Some clinical studies suggest benefit)
• Sinus congestion and thick mucus (Some clinical studies suggest benefit, though trials are small)
• General aches and stiffness (Early research only)
• Post-dental procedure comfort (Some clinical studies suggest benefit)

Suggested to use alongside

• Bromelain: Another proteolytic enzyme
• Turmeric: Popular golden spice supplement
• MSM: Popular joint comfort nutrient

Serrapeptase (also called serratiopeptidase) is a metalloprotease produced by the bacterium Serratia marcescens E15. It is a zinc-containing enzyme of about 52 kDa. It cuts proteins at specific sites, and it is measured in enzyme activity units (SPU) rather than only in milligrams, so activity matters more than weight.

In laboratory and animal studies, it has been reported to break down inflammatory mediators such as bradykinin, and to reduce the formation of fibrin, a protein involved in clotting and swelling. It also appears to thin and reduce the viscosity of mucus, which may help clear the airways. These effects are the basis of the traditional uses.

Absorption. A major question is how a large enzyme reaches the bloodstream. Animal studies suggest that small amounts may cross the intestinal wall intact, but human data are limited. Stomach acid denatures the enzyme, so enteric-coated capsules that open in the intestine are important. It is usually taken on an empty stomach so food does not compete with it.

Several small trials from the 1990s to 2000s, including studies after dental surgery (Esch et al., Journal of Oral and Maxillofacial Surgery, 1989), reported reduced swelling. Modern, large and well-controlled trials are lacking, so the evidence base should be considered preliminary. Examine.com and review articles generally rate it as promising but unproven.

• Pack size: 270 Caps
• Form: Vegetarian capsules

Supplement Facts

Serving Size: 1 Veggie Capsule

Servings Per Container: 270

Amount per serving: % Daily Value

Calcium (from tricalcium phosphate and calcium stearate in Serrateric™): 35 mg 3%

Science-Based Nutrition™ Dietary Supplement Non-GMO / Vegan Helps Support Healthy Sinuses Helps Breakdown Unwanted Proteins Serrapeptase (serratio-peptidase) is a protein-digesting enzyme isolated from the friendly bacterium Serratia E-15 discovered in the Japanese silkworm, and has been used as a nutritional supplement in Europe and Asia for decades. Doctor's Best Serrapeptase 120,000 SPU is formulated with Serrateric™, a superior alternative to enteric coating that protects the individual enzyme until it reaches the intestine for optimal absorption.

Suggested Use

Adult Use: Take 1 capsule daily with at least 8 oz. of water on an empty stomach, or as recommended by a nutritionally informed physician. First time users may benefit from starting with lower dosage Serrapeptase 40,000 SPU.

INGREDIENTS

Serrateric™ (maltodextrin, tricalcium phosphate, calcium stearate, microcrystalline cellulose, medium chain triglycerides), delayed release vegetarian capsule (hypromellose, gellan gum, purified water).

Warnings

Keep out of reach of children. in a cool dry place.

Always read the label and follow the directions for use. This information is general in nature and not medical advice. If symptoms persist, talk to your health professional.

Supplier ref: High Potency Serrapeptase, 120,000 SPU, 270 Veggie Caps

What is serrapeptase?

Serrapeptase is a protein-digesting enzyme originally found in silkworm gut bacteria. It is now made by fermentation for use in supplements.

What is serrapeptase used for?

It is used to support comfort after minor injury or exercise, to help support a normal inflammatory response and to support airway comfort.

When is the best time to take serrapeptase?

Take it on an empty stomach, at least 30 minutes before a meal or two hours after, with a glass of water.

Why does serrapeptase need to be enteric-coated?

Stomach acid can break the enzyme down. An enteric coating protects it until it reaches the intestine.

How long does serrapeptase take to work?

Most people use it for two to four weeks before judging. Studies on post-procedure swelling saw effects within days.

Can I take serrapeptase with other supplements?

It is often combined with bromelain, turmeric or nattokinase. Check with your practitioner if you take other enzymes that affect blood clotting.

Serrapeptase may have a mild blood-thinning effect, so avoid it if you take warfarin, aspirin or similar medicines unless advised by your healthcare professional, and stop at least two weeks before surgery. Avoid in pregnancy and breastfeeding. Mild stomach upset, rash or cough can occur. Do not use if you have a bleeding disorder.

Doctor's Best is an American brand focused on science-based nutrition.

HerbalHealth.Shop is your friendly Australian home for natural health. We bring together a huge range of trusted vitamins, herbs and natural skin care, from the world's best-known brands to small family-owned businesses and handmade makers we're proud to support.