Vitamin B12, 500mcg, 250 Caps

Benefits

• Helps maintain normal energy-yielding metabolism.
• Helps support the normal function of the nervous system.
• Helps in the formation of healthy red blood cells.
• Helps relieve tiredness and fatigue when dietary intake is inadequate.
• Helps maintain normal homocysteine metabolism.
• Essential for those following vegan or vegetarian diets.

What people commonly use it for

• Tiredness and low energy (Good clinical evidence when intake is low)
• Pins and needles from low intake (Good clinical evidence when linked to low B12)
• Plant-based diets (Good clinical evidence that supplements maintain B12 levels)
• Brain fog and low mood from low B12 (Some clinical studies suggest benefit only when levels are low)
• Reduced absorption with age (Good clinical evidence that supplements are well absorbed)

Suggested to use alongside

• B complex: Other B vitamins that work together with B12
• Folate: Works with B12 in normal red blood cell formation
• Iron: Mineral that supports normal red blood cell production

Vitamin B12 (cobalamin) is a cobalt-containing vitamin that works as a coenzyme in two key reactions. In the first, methylcobalamin helps convert homocysteine to methionine, working alongside folate. In the second, adenosylcobalamin helps convert methylmalonyl-CoA to succinyl-CoA, which is part of energy metabolism from fats and proteins.

Absorption. In food, B12 is bound to protein. Stomach acid and enzymes free it, and it then binds to intrinsic factor, a protein made by the stomach, to be absorbed in the last part of the small intestine. Because this pathway is limited, only a small amount is absorbed from a single dose. However, about 1 percent of a high dose is absorbed by passive diffusion without intrinsic factor, which is why oral supplements work for many people (NIH Office of Dietary Supplements).

Forms. Cyanocobalamin is the most stable and widely studied. Methylcobalamin and adenosylcobalamin are the active coenzyme forms, and hydroxocobalamin is a natural form. All are converted to active B12 in the body.

Low intake. The body stores several years' worth of B12 in the liver, so shortfalls develop slowly. Signs can include tiredness, pale skin, tingling in the hands and feet, and a sore tongue.

• Pack size: 250 Caps
• Strength: 500mcg
• Form: Capsules

Since 1947 Energy Metabolism Nervous System Support Non-GMO Certified Gluten Free Wheat & Dairy Free Suitable for Vegans Kosher Parve Dietary Supplement Vitamin B12 is part of a group of essential nutrients known as the B Complex. It supports energy metabolism and promotes a healthy nervous system. Along with Folic Acid and Vitamin B6, it supports heart health by promoting healthy levels of homocysteine already within a normal range. B12 is required for the normal development and regeneration of red bloods cells, which help to deliver oxygen throughout the body.

Supplement Facts

Serving Size: 1 Vegetable Capsule

Amount Per Serving: %DV

Vitamin B12 (as cyanocobalamin): 500 mcg 20,833%

Free of: Gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and color.

Warnings

If you are pregnant, nursing, taking any medications or have any medical condition, please consult your healthcare practitioner before taking any dietary supplement. Discontinue use and consult your healthcare practitioner if any adverse reactions occur. Keep out of reach of children. at room temperature. Do not use if outer bottle seal is missing or damaged.

Always read the label and follow the directions for use. This information is general in nature and not medical advice. If symptoms persist, talk to your health professional.

Supplier ref: Vitamin B12, 500 Mcg, 250 Vegetable caps

What does vitamin B12 do?

B12 supports energy metabolism, the nervous system and the formation of red blood cells. It also helps process homocysteine.

Which form of B12 is best?

Cyanocobalamin is stable and well studied, while methylcobalamin is the active form. Both raise B12 levels, so choose one that suits your preference.

Who is most likely to need B12?

People following vegan or vegetarian diets, older adults and those with reduced stomach acid. Some medicines can also lower absorption.

When is the best time to take B12?

Many people take it in the morning, since B12 may feel energising. Take it with or without food as per your label.

How long does B12 take to work?

If your levels were low, you may notice more energy within a few weeks. Full replenishment can take a few months.

Can you take too much B12?

B12 is water soluble and excess is generally excreted. Stick to the label and ask your health professional about high doses.

B12 is generally well tolerated. Speak to your health professional before use if you take metformin, acid-reducing medication or have a history of Leber's eye disease. Ask to have your levels tested if you have persistent tiredness.

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